My MCAS flairs mimic HyperPOTS but surprisingly my actual POTS isn’t HyperPOTS. So if my blood pressure also skyrockets, for me it’s MCAS. My cardiologist is very versed on MCAS and POTS and he even has a hard time distinguishing the two since MCAS patients are more likely to have HyperPOTS. My POTS is likely secondary to EDS and Chiari Malformation.

with MCAS i get more allergy symptoms of tight chest and congestion and itchiness; hives are a big tell too. POTS is more lightheaded for me!