Understanding Acroangiodermatitis: Causes, Symptoms, and Management

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Acroangiodermatitis

by Alike Medical Team ∙ Updated on June 13, 2023

Additional names

This group contains additional names: - Pseudoxanthoma elasticum-like papillary dermal elastolysis - Gracely's syndrome

General

Acroangiodermatitis, also known as pseudoxanthoma elasticum-like papillary dermal elastolysis or Gracely's syndrome, is a rare skin condition characterized by the progressive degeneration of elastic fibers in the skin, as well as the formation of papules and plaques. It is most commonly seen in individuals with chronic venous insufficiency, arteriovenous malformations, or lymphatic obstruction.

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Signs & symptoms

Symptoms of acroangiodermatitis typically begin with the appearance of small, red, and papular lesions on the skin of the feet and legs. These lesions can develop into larger, darker, and more elevated plaques over time. In some cases, they may also become ulcerated or infected. Other associated symptoms may include pain, itching, and swelling.

Diagnosis

The diagnosis of acroangiodermatitis is typically made through a combination of clinical examination and skin biopsy. The skin biopsy will reveal characteristic changes in the elastic fibers of the skin, as well as the presence of inflammatory cells.

Treatment

There is no specific treatment for acroangiodermatitis, and management is generally focused on addressing any underlying conditions that may be contributing to the development of the skin lesions. This may include compression therapy for venous insufficiency, surgical intervention for arteriovenous malformations, or lymphatic drainage for lymphatic obstruction. In some cases, topical or systemic corticosteroids may be used to alleviate symptoms such as pain and itching.

Note

☝ We provide information on prescription and over-the-counter medicines, diagnosis, procedures and lab tests. This material is provided for educational purposes only and is not medical advice, diagnosis or treatment.

National Institutes of Health ∙ World Health Organization ∙ MedlinePluse ∙ Centers for Disease Control and Prevention

☝ All information has been reviewed by certified physicians from Alike

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