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Selective IgM immunodeficiency
Selective IgM immunodeficiency
by Alike Medical Team ∙ Updated on June 13, 2023
General
Selective IgM deficiency is an immune system condition in which the person lacks immunoglobulin M, while all other immunoglobulin levels are normal. Immunoglobulin M is a protein that is part of the immune system. This condition is rare, and may occur as a primary condition (on its own), or combined with other conditions (more commonly). People with selective IgM deficiency tend to suffer from other autoimmune conditions such as rheumatoid arthritis, lupus, celiac disease and inflammatory bowel disease.
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Signs & symptoms
Diagnosis of selective IgM deficiency is suspected when there are recurrent infections, autoimmune diseases, chronic diarrhea or a combination of these conditions. To establish the diagnosis, blood tests should demonstrate undetected IgM levels.
Diagnosis
People who have selective IgM deficiency may experience recurrent infections (ear, bronchitis, sinusitis, pneumonia), diarrhea, skin rash, allergies and asthma.
Treatment
There is no cure for IgM deficiency. treatment is by treating the symptoms, for example- treating recurrent infections with prophylactic antibiotics.
Note
☝ We provide information on prescription and over-the-counter medicines, diagnosis, procedures and lab tests. This material is provided for educational purposes only and is not medical advice, diagnosis or treatment.
National Institutes of Health ∙ World Health Organization ∙ MedlinePluse ∙ Centers for Disease Control and Prevention
☝ All information has been reviewed by certified physicians from Alike
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