I took that for a long time like almost 3 years and I still had issues with very high anxiety. I finally convinced my dr to change my medication and im finally starting to feel better. Just be warned when you stop taking venlafaxine you go through what my therapist called emotional withdrawal. I would be driving down the highway and start crying hysterically for no reason.

I went through the same thing. It was the best for my pain and fatigue but I was crazy with anxiety. Have you tried Desvenlafaxine? It's a little calmer than venlafaxine which makes a little less effective but still it's helping a lot