I am on a mixture of meds. I can share if you want? I mean they work for me. But person is so different. Each flare up can be different.

If your comfortable sharing please do!! Because I'm at my wits end! I use medical marijuana on top of the gabapentin and oxycodone for pain and without the gabapentin I feel like my whole body is on fire 24/7 and I have what I call tazer shocks all over my body 100times worse than they used to be!

I understand completely. Cymbalta is great, Amitriptyline, and a good muscle relaxer. I also do aqua therapy.

I'm on low dose naltrexone

Cymbalta

I take Methocarbomal, Meloxicam and two natural products (Fibralgia and IR relief) - it doesn't take it away, but makes me a little more functional if I don't take anything.

Methocarbamal is generic Robaxan. It is a muscle relaxer with a pain reliever. Meloxicam is generic Mobic. It is am anti-inflammatory and treats artists. I take both of these. The Naltrexon treats addiction. For you, it helps you not get addicted to the hydrocodone by blocking the receptors that make you feel high. Someone else m8ght know more about this one.

Naltrexone is the cousin drug of Methadone, Naloxone, and Suboxone/Buprenorphine. These meds were primarily used to treat opiate dependency as it is what's known as a partial opioid antagonist. Basically, it fits in the opiate receptors in the same way a true opiate would. Because of this, some people find pain relief from this. For Fibromyalgia, Naltrexone is prescribed in a low dose form. This low dose form has to be custom made at a compound pharmacy which can make it tricky to get covered by insurance. Suboxone/Buprenorphine would be more readily available and works in a similar fashion. However, you would have to go through a Medication Assisted Treatment program to be monitored closely. Similar to most meds prescribed for Fibromyalgia, these meds can have serious side effects that can be intolerable when starting. Some people also have sensitivity to the adhesive in the Buprenorphine topical patches.

I've found every few years my muscle relaxers become immune so I have to switch it up. I've been on Cyclobenzaprine/ Flexeril, Baclofen (briefly, couldn't tolerate), Tizanidine/ Zanaflex, and now on Methocarbamol/Robaxen.

Have you tried any injections like epidural steroid injections or trigger point injections? Or topical medications at all. I once did a trial of Clonidine which is sometimes used off label for Fibromyalgia.