I have had the most success with fludrocortisone and atenolol medication wise. Hydration with electrolytes (I like Liquid IV and DripDrop) has been amazing (my gastroparesis has been making this hard lately, and my POTS is definitely flaring because of it). I did IV fluids for about a year, and it was great (I did a liter 3-4 days a week). I also recommend compression socks and a shower chair. And don’t be afraid of mobility aids if you think they would be helpful. Best of luck!! :)

I take fludrocortizone as well. in addition to that I take prazosin as a beta blocker

Florinef helped for around a year, then stopped being as effective. I started Atenolol 2 months ago and it has helped more than Florinef did. With Atenolol + physical therapy, I am now able to exercise, while keeping my heart rate and blood pressure stable. I no longer feel my heart beating out of my chest and can sweat normally now. I am able to go 10 minutes on a treadmill - before, I failed 2 stress tests. I’ve tried the classic Midodrine, IV fluids, etc. None of them worked. I am always constantly lightheaded/woozy and they suspect I have craniocervical instability (CCI) alongside of POTS.

Physical therapy (core and lower body workouts) and salt sticks! I got IV fluids for a while too but have been able to stop since the PT

I cannot say physical therapy enough!!! I also take midodrine 3-4 times daily. High salt intake. Clean diet(as appetite allows). Liquid IV is a life saver- got me through nursing school. I drink one every morning. Two or three on flare days. (There's a dysautonomia code for 30%off)

I’ve found that putting midodrine and metropalol together works well for my symptoms