I’m into year 2 with UCTD/MCTD and I’m on Plaquenil and Methotrexate now for about 4 months. The methotrexate immediately helped my fatigue but it took about 3 months to help my flares. I think the major thing with me is that when I get stressed out, I flare. I am trying to work on that. What symptoms do you have? I think what I’ve done is exercise as much as I can (I walk), try to engage in social things (mostly family things for me), I also go to school as best as I can. It’s really hard though. We can only do what we can do. Try not to feel bad about your limitations. Give yourself grace and room to figure out what you can and can’t do. Feel free to message me!