On my! Yes ! I have been on plaquenil for almost 3 years and have had to make adjustments. Do you mind me asking you your dose? To avoid nausea / not being able to eat. If it’s the weekend and I have to double my dose I do I do one in the am ( 1-2 hours after my synthroid with my breakfast) then one at lunch or with a pm snack. I have a hard time sleeping if I take it after 3pm If it’s a weekday and it’s half the dose I take then I only take in AM with breakfast. If you can tolerate dairy it’s helpful to take it with dairy

Feel free to message me! Plaquenil has been so so life changing but it keeps me on my toes lol

Can Plaquenil produce reflux?

It gets in the way of sleep?

For me, I wasn’t able to fall asleep when I take it late in the afternoon. I was informed it could cause sleep difficulties / weird dreams but wasn’t a major side effect. My friend who is on it has no issues taking in at dinner time/ later in the day.

Indigestion/ nausea I believe is the most common side effect.

I was recently reduced from 200mg 2x a day to just 200mg once a day. It has caused me to lose so much weight

Yes I had that same issue. Hopefully the stomach symptoms resolve with once a day & taking it with food/dairy if able

I can eat in the morning. Late afternoon/evening is when the nausea gets really bad. I end up drinking an Ensure because I can’t tolerate anything else