Can you take an injectable? The longer you're in pain, the more damage is happening. I was un medicated for 2-3 months from the on-set to Ruematologist appointment. The pain was unbearable. I am now on humira once a week. Sooo happy. I have no experience with methotrexate. I started out with and stayed with humira.

I'm on weekly injection of Methotrexate. I got mild nausea and headaches. Went away gradually. I just decided headache and nausea better than the damage to my joints without.

All of the immunosuppresants i have ever taken for my Psoriatic arthritis has made me so ill. I have tried 4 or 5 different ones over the last year, never again, personally.

I'm taking methotrexate. Some nausea and headaches initially but that got better. I also take Lyrica and Tramadol. Sorry you're having such a hard time. I have also had relief with warm Parafin dips. They have machines or a crock pot works to melt the wax. You can add essential oil. I also have warming mitts for hands and feet. Kind of like heating pads for your hands and feet. Wishing you pain relief. 💜💜💜💜

I too was afraid and asked for something else. I’m now on Otezla and Cosentyz injections once a month. I’m having good results.

It sucks!! It didn't work for me but unfortunately our medical needs n wants are 2 different things. You have to fail so many meds in order to get a biologic/injection. I failed 7 medications before getting Tremfya injection 💉. I'm on it almost 6m and I see SOME results but not 100%. Nothing will ever be. Good luck in whatever you try!!

I'm taking methotrexate, orally. Have some relief but not significant enough. They just increased my dosage this week. I take the folic acid every day as recommended to by my rheumatoid dr. Have never had any nausea from it. Maybe slight headache but not too bad.

i take metho weekly at a .7 ml dose and it is extremely helpful for me combined with my humira weekly mostly i just get some nausea and headaches usually people get bad experiences with metho when they’re on too big of a dose starting out you need to ease into it slowly increasing for best results in my experience

i take the shot version and i would recommend that over the other options as long as you are okay with giving yourself injections

I take cosentyx twice a month and it seems to be the only thing that helped my psoriatic arthritis until now! Now I have sores on almost all my fingers and they are super painful!!