Mirapex or generic name Pramipexole is a godsend! I've used the med for years. Before the RLS got so bad, tonic water with quinine helped but it takes a lot of it, drank some time before bed. There was, with the over the counter sleep meds, a product for legs. One has quinine & one doesn't. The quinine works but I've noticed it is hard to find now. A hot soak in the bathtub before bed can help, the water as hard as you can stand without scalding yourself. RLS is one tough disease! Best of luck to you. May Spirit bless you.