I take buspirone and escitalopram (lexapro). I'm also on lamotrigine (lamictal) for seizures, but it's also used as a mood stabilizer in people without epilepsy. My psychiatrist added buspirone when the Lexapro wasn't enough, and between those three and one other, both my depression/anxiety and my seizures are under control. My psychiatrist had a different one he said is most often prescribed with Lexapro, but due to my epilepsy he had to prescribe buspirone instead. I've only been on it for about 2 months and there is a significant and noticeable difference. Obviously what works for me might not work for you, but that's where I am with the buspirone.