My husband is currently on it. He said he noticed a difference immediately, but his anxiety was really out of hand.

I didn't personally notice a difference. My system didn't react even after 3 weeks of taking the meds. My sister however, she had better luck with her anxiety. (She doesn't have ADHD though)

It didn’t help at all. Went off cold turkey after 10 months of zero improvement

The Wellbutrin didn’t help my depression at all. I saw decent ADD improvement but I’m also taking adderall which has been like a miracle drug for me. I switched to Wellbutrin from Zoloft because of the sexual side effects. The Wellbutrin was good in that way but for my brain anyway not much help with depression. But everybody is different, maybe after a few weeks it will kick in for him? Good luck.

I haven't had problems with it. I don't think it's helped my mood much, but it is helping me cut back on smoking